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Bugs, Gut, and Glial

Advancing Understanding of Nutrition’s Role in…..Well….Everything

Gratitude filled my heart after being able to take part in the pre-conference course sponsored by the APTA Orthopedic Section’s Pain Management Special Interest Group this past February. For two days, participants heard from leaders in the field of progressive pain management with integrative topics including neuroscience, cognitive behavioral therapy, motivational interviewing, sleep, yoga, and mindfulness to name a few. It’s exciting to witness and participate in the evolution of integrative thinking in physical therapy. When it was my turn to deliver the presentation, I had prepared about nutrition and pain, I could hardly contain my passion. While so much of our pain-related focus is placed on the brain, I realized acutely the stone yet unturned is the involvement of the enteric nervous system (aka the gut) on pain and….well…everything.

Much appreciation is due to those on the forefront of pain sciences for their research, their insight, their tireless work to fill our tool boxes with pain education concepts. Neuroscience has made tremendous leaps and bounds as has corresponding digital media to help explain pain to our patients. One such brilliant 5-minute tool can be found on the Live Active YouTube channel.

What I love about this video is how intelligently (and artistically!) it puts into accessible language some incredibly complex processes. It even mentions lifestyle and nutrition as playing a role in what is commonly referred to as a maladaptive central nervous system.

"Maladaptive central nervous system"

Ok. I’ll admit, I struggle with the implications of this term. However, what doesn’t sit right with me is the concept of chronic or persistent pain being entirely in the brain as though the brain is a static entity. We know the brain to be plastic but often do not identify just how this is so.

Glial Cells found in Nervous SystemWhat about the role of our second brain…. the one with 200-600 million neurons that live in that middle part of our body (right next to / inside our pelvis)? Termed the enteric nervous system, this second brain both stores and produces neurotransmittersTurna, et.al., 2016, serves as the scaffolding of interplay between the ENS, SNS, and CNS. This ENS is home to the interface of “bugs, gut, and glial” which are “not only in anatomical proximity, but also influence and regulate each other…interconnected for mutual homeostasis.”Lerner, et.al., 2017 In fact, part of this process then directly impacts the brain. “Healthy brain function and modulation are dependent upon the microbiota’s [gut bugs] activity of the vagus nerve.”Turna, et.al., 2016. Further, “by direct routes or indirectly, through the gut mucosal system and its local immune system, microbial factors, cytokines, and gut hormones find their ways to the brain, thus impacting cognition, emotion, mood, stress resilience, recovery, appetite, metabolic balance, interoception and PAIN.”Lerner, et.al., 2017

So, by process of logic, it requires little convincing to conclude that the food we eat or fail to eat directly impacts the health or dysfunction of this magnificently orchestrated system. One that directly and profoundly impacts our brain, our body, our being. And it’s a concept that our patients, our clients, ourselves, know in our gut to be true.

And it’s thanks to all the hard work of those who have come before us that we can share in the advancing understanding for the benefit of thousands who need your help, expertise and guidance. Please join me for Nutrition Perspectives for the Pelvic Rehab Therapist. The next course will be in Springfield, MO on June 23-24, 2018. Vital and clarifying information awaits you!


Live Active. (2013, Jan) Understanding Pain in less than 5 minutes, and what to do about it! https://www.youtube.com/watch?v=C_3phB93rvI Retrieved March 28, 2018.
Lerner, A., Neidhofer, S., & Matthias, T. (2017). The Gut Microbiome Feelings of the Brain: A Perspective for Non-Microbiologists. Microorganisms, 5(4). doi:10.3390/microorganisms5040066
Turna, J., Grosman Kaplan, K., Anglin, R., & Van Ameringen, M. (2016). "What's Bugging the Gut in Ocd?" a Review of the Gut Microbiome in Obsessive-Compulsive Disorder. Depress Anxiety, 33(3), 171-178. doi:10.1002/da.22454

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Upcoming Continuing Education Courses

Mobilization of the Myofascial Layer - Medford, OR Satellite Location

Nov 6, 2020 - Nov 8, 2020
Location: Asante Rogue Valley Medical Center

Nutrition Perspectives for the Pelvic Rehab Therapist - Seattle, WA (POSTPONED)

Nov 6, 2020 - Nov 8, 2020
Location: MTI Physical Therapy

Mobilization of the Myofascial layer: Pelvis and Lower Extremity- Greenville, SC (Postponed)

Nov 6, 2020 - Nov 8, 2020
Location: Bon Secours St. Francis Health System

Mobilization of the Myofascial Layer Satellite Lab Course

Nov 6, 2020 - Nov 8, 2020
Location: Replacement Remote Course

Mobilization of the Myofascial Layer - Athens, GA Satellite Location

Nov 6, 2020 - Nov 8, 2020
Location: Thrive Integrated Medicine

Mobilization of the Myofascial Layer - Greenville, SC Satellite Location

Nov 6, 2020 - Nov 8, 2020
Location: Bon Secours St. Francis Health System

Mobilization of Myofascial - Self-Hosted

Nov 6, 2020 - Nov 8, 2020
Location: Self-Hosted Course

Nutrition Perspectives for the Pelvic Rehab Therapist - Remote Course

Nov 7, 2020 - Nov 8, 2020
Location: Replacement Remote Course

Athletes & Pelvic Rehabilitation - San Diego, CA (Postponed)

Nov 7, 2020 - Nov 8, 2020
Location: Comprehensive Therapy Services

Pelvic Floor Level 2B - Somerset, NJ Satellite Course

Nov 7, 2020 - Nov 8, 2020
Location: Sports Medicine Institute

Pelvic Floor Level 2A - Grand Rapids, MI (SOLD OUT)

Nov 7, 2020 - Nov 8, 2020
Location: Mary Free Bed Rehabilitation Hospital

Pregnancy Rehabilitation - Washington, DC (Postponed)

Nov 7, 2020 - Nov 8, 2020
Location: GWUH Outpatient Rehabilitation Center

Bowel Pathology and Function -Middletown, CT (Postponed)

Nov 7, 2020 - Nov 8, 2020
Location: Middlesex Hospital

Bowel Pathology and Function - Remote Course

Nov 7, 2020 - Nov 8, 2020
Location: Replacement Remote Course

Pregnancy Rehabilitation - Remote Course (SOLD OUT)

Nov 7, 2020 - Nov 8, 2020
Location: Replacement Remote Course

Pelvic Floor Level 2B - Satellite Lab Course

Nov 7, 2020 - Nov 8, 2020
Location: Replacement Remote Course

Pelvic Floor Level 2B - Marietta, GA Satellite Location (SOLD OUT)

Nov 7, 2020 - Nov 8, 2020
Location: Southern Pelvic Health

Pelvic Floor Level 2B - East Norriton, PA Satellite Course

Nov 7, 2020 - Nov 8, 2020
Location: Core 3 Physical Therapy

Pelvic Floor Level 2B - Cranford, NJ Satellite Course

Nov 7, 2020 - Nov 8, 2020
Location: Ivy Rehab Physical Therapy

Pelvic Floor Level 2B - Manchester, IA Satellite Course

Nov 7, 2020 - Nov 8, 2020
Location: Physical Therapy Solutions

Pelvic Floor Level 2B - Richmond, VA Satellite Course

Nov 7, 2020 - Nov 8, 2020
Location: Pivot Physical Therapy

Athletes & Pelvic Rehabilitation - Remote Course

Nov 7, 2020 - Nov 8, 2020
Location: Replacement Remote Course

Pelvic Floor Level 2B - Self-Hosted

Nov 7, 2020 - Nov 8, 2020
Location: Self-Hosted Course

Pelvic Floor Level 2A - Bay Shore, NY (Postponed)

Nov 8, 2020 - Nov 9, 2020
Location: Touro College: Bayshore

Mobilization of Visceral Fascia: The Gastrointestinal System - Jackson, WY Satellite Location

Nov 13, 2020 - Nov 15, 2020
Location: Four Pines Physical Therapy

Mobilization of Visceral Fascia: The Gastrointestinal System - Fairlawn, NJ (Postponed)

Nov 13, 2020 - Nov 15, 2020
Location: Bella Physical Therapy

Mobilization of Visceral Fascia: The Gastrointestinal System - Self-Hosted

Nov 13, 2020 - Nov 15, 2020
Location: Self-Hosted Course

Mobilization of Visceral Fascia: The Gastrointestinal System - Fargo, ND Satellite Location

Nov 13, 2020 - Nov 15, 2020
Location: Apex Physical Therapy & Wellness Center